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Langerhans cells and SFRP2/Wnt/beta‐catenin signalling control adaptation of skin epidermis to mechanical stretching

Skin can be mechanically stimulated to grow through a clinical procedure called tissue expansion (TE). Using a porcine TE model, we determined that expansion promptly activates transcription of SFRP2 in skin and we revealed that in the epidermis, this protein is secreted by Langerhans cells (LCs). S...

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Detalles Bibliográficos
Autores principales:	Ledwon, Joanna K., Vaca, Elbert E., Huang, Chiang C., Kelsey, Lauren J., McGrath, Jennifer L., Topczewski, Jacek, Gosain, Arun K., Topczewska, Jolanta M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817127/ https://www.ncbi.nlm.nih.gov/pubmed/35019227 http://dx.doi.org/10.1111/jcmm.17111

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