Acute post-injury blockade of α2δ−1 calcium channel subunits prevents pathological autonomic plasticity after spinal cord injury

After spinal cord injury (SCI), normally innocuous visceral or somatic stimuli can trigger uncontrolled reflex activation of sympathetic circuitry, causing pathological dysautonomia. We show that remarkable structural remodeling and plasticity occur within spinal autonomic circuitry, creating abnorm...

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Detalles Bibliográficos
Autores principales: Brennan, Faith H., Noble, Benjamin T., Wang, Yan, Guan, Zhen, Davis, Hayes, Mo, Xiaokui, Harris, Clay, Eroglu, Cagla, Ferguson, Adam R., Popovich, Phillip G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817229/
https://www.ncbi.nlm.nih.gov/pubmed/33503436
http://dx.doi.org/10.1016/j.celrep.2020.108667

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