Protective activity of mRNA vaccines against ancestral and variant SARS-CoV-2 strains

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Although mRNA vaccines encoding the spike protein of SARS-CoV-2 prevent COVID-19, the emergence of new viral variants jeopardize their efficacy. Here, we assessed the immunogenicity and protective activity of historical (mRNA-1273, designed for Wuhan-1 spike protein) or modified (mRNA-1273.351, desi...

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Detalles Bibliográficos
Autores principales: Ying, Baoling, Whitener, Bradley, VanBlargan, Laura A., Hassan, Ahmed O., Shrihari, Swathi, Liang, Chieh-Yu, Karl, Courtney E., Mackin, Samantha, Chen, Rita E., Kafai, Natasha M., Wilks, Samuel H., Smith, Derek J., Carreño, Juan Manuel, Singh, Gagandeep, Krammer, Florian, Carfi, Andrea, Elbashir, Sayda M., Edwards, Darin K., Thackray, Larissa B., Diamond, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817234/
https://www.ncbi.nlm.nih.gov/pubmed/34846168
http://dx.doi.org/10.1126/scitranslmed.abm3302
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