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Glucagon signaling via supraphysiologic GCGR can reduce cell viability without stimulating gluconeogenic gene expression in liver cancer cells

BACKGROUND: Deregulated glucose metabolism is a critical component of cancer growth and survival, clinically evident via FDG-PET imaging of enhanced glucose uptake in tumor nodules. Tumor cells utilize glucose in a variety of interconnected biochemical pathways to generate energy, anabolic precursor...

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Detalles Bibliográficos
Autores principales:	Godfrey, Jason, Riscal, Romain, Skuli, Nicolas, Simon, M. Celeste
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817478/ https://www.ncbi.nlm.nih.gov/pubmed/35123542 http://dx.doi.org/10.1186/s40170-022-00280-1

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