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Long-term running exercise improves cognitive function and promotes microglial glucose metabolism and morphological plasticity in the hippocampus of APP/PS1 mice

BACKGROUND: The role of physical exercise in the prevention of Alzheimer’s disease (AD) has been widely studied. Microglia play an important role in AD. Triggering receptor expressed in myeloid cells 2 (TREM2) is expressed on microglia and is known to mediate microglial metabolic activity and brain...

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Detalles Bibliográficos
Autores principales:	Zhang, Shan-shan, Zhu, Lin, Peng, Yan, Zhang, Lei, Chao, Feng-lei, Jiang, Lin, Xiao, Qian, Liang, Xin, Tang, Jing, Yang, Hao, He, Qi, Guo, Yi-jing, Zhou, Chun-ni, Tang, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817568/ https://www.ncbi.nlm.nih.gov/pubmed/35123512 http://dx.doi.org/10.1186/s12974-022-02401-5

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