Cargando…

Membrane progesterone receptor α (mPRα) enhances hypoxia-induced vascular endothelial growth factor secretion and angiogenesis in lung adenocarcinoma through STAT3 signaling

Lung cancer remains a huge challenge to public health because of its high incidence and mortality, and lung adenocarcinoma (LUAD) is the main subtype of lung cancer. Hypoxia-induced vascular endothelial growth factor (VEGF) release and angiogenesis have been regarded as critical events in LUAD carci...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xia, Zhi, Xiao, Jian, Dai, Ziyu, Chen, Qiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817580/ https://www.ncbi.nlm.nih.gov/pubmed/35123491 http://dx.doi.org/10.1186/s12967-022-03270-5

Ejemplares similares

Expression and Purification of Human Membrane Progestin Receptor α (mPRα)
por: Hossain, Md. Babul, et al.
Publicado: (2015)

Progesterone exerts a neuroprotective action in a Parkinson’s disease human cell model through membrane progesterone receptor α (mPRα/PAQR7)
por: Castelnovo, Luca F., et al.
Publicado: (2023)

Data on RT-qPCR assay of nuclear progesterone receptors (nPR), membrane progesterone receptors (mPR) and progesterone receptor membrane components (PGRMC) from human uterine endometrial tissue and cancer cells of the Uterine Cervix
por: Smaglyukova, Natalia, et al.
Publicado: (2020)

Hypoxia-induced angiogenesis and vascular endothelial growth factor secretion in human melanoma.
por: Rofstad, E. K., et al.
Publicado: (1998)

mPR-Specific Actions Influence Maintenance of the Blood–Brain Barrier (BBB)
por: Abou-Fadel, Johnathan, et al.
Publicado: (2022)

RF15 | PMON305 Membrane Progesterone Receptor α (mPRα/PAQR7) Promotes Survival and Axonal Sprouting in Human Neuronal Cells Lines Through Direct and Human Schwann-Cell Like Differentiated Adipose Stem Cells-Mediated Mechanisms
por: Castelnovo, Luca F, et al.
Publicado: (2022)

Multiple Primary Recurrent Basaliomas (mPR-BCCs) of the Scalp with Cranial Bone Invasion
por: Tchernev, Georgi, et al.
Publicado: (2017)

Membrane progesterone receptor beta (mPRβ/Paqr8) promotes progesterone-dependent neurite outgrowth in PC12 neuronal cells via non-G protein-coupled receptor (GPCR) signaling
por: Kasubuchi, Mayu, et al.
Publicado: (2017)

Role of mprF1 and mprF2 in the Pathogenicity of Enterococcus faecalis
por: Bao, Yinyin, et al.
Publicado: (2012)

Rapamycin Antagonizes BCRP-Mediated Drug Resistance Through the PI3K/Akt/mTOR Signaling Pathway in mPRα-Positive Breast Cancer
por: Zhang, Jing, et al.
Publicado: (2021)

Adrenomedullin promotes angiogenesis in epithelial ovarian cancer through upregulating hypoxia-inducible factor-1α and vascular endothelial growth factor
por: Zhang, Yi, et al.
Publicado: (2017)

Understanding End-User Perspectives of Mobile Pulmonary Rehabilitation (mPR): Cross-Sectional Survey and Interviews
por: Dobson, Rosie, et al.
Publicado: (2019)

Rejection and killing, without MPR
por: Dove, Alan W.
Publicado: (2003)

Hypoxia-inducible factor-1α and vascular endothelial growth factor in the cardioprotective effects of intermittent hypoxia in rats
por: Wang, Zhang, et al.
Publicado: (2013)

Tanshinone I inhibits tumor angiogenesis by reducing STAT3 phosphorylation at TYR705 and hypoxia-induced HIF-1α accumulation in both endothelial and tumor cells
por: Wang, Yan, et al.
Publicado: (2015)

Effects of Tetrahydrocurcumin on Hypoxia-Inducible Factor-1α and Vascular Endothelial Growth Factor Expression in Cervical Cancer Cell-Induced Angiogenesis in Nude Mice
por: Yoysungnoen, Bhornprom, et al.
Publicado: (2015)

Enzyme 15-lipoxygenase 1 promotes hypoxia-inducible factor 1α turnover and reduces vascular endothelial growth factor expression: implications for angiogenesis
por: Zhong, Hua, et al.
Publicado: (2014)

Intrabody against prolyl hydroxylase 2 promotes angiogenesis by stabilizing hypoxia-inducible factor-1α
por: Zhao, Liangzhong, et al.
Publicado: (2019)

Cinobufagin suppresses colorectal cancer angiogenesis by disrupting the endothelial mammalian target of rapamycin/hypoxia‐inducible factor 1α axis
por: Li, Xiaowu, et al.
Publicado: (2019)

The effects of black cohosh on the regulation of estrogen receptor (ERα) and progesterone receptor (PR) in breast cancer cells
por: Szmyd, Monica, et al.
Publicado: (2018)

Expression of hypoxia-inducible factor-1α and vascular density in mammary adenomas and adenocarcinomas in bitches
por: Madej, Janusz A, et al.
Publicado: (2013)

Hypoxia-Inducible Factor-1α: The Master Regulator of Endothelial Cell Senescence in Vascular Aging
por: Alique, Matilde, et al.
Publicado: (2020)

Paeoniflorin alleviates the progression of retinal vein occlusion via inhibiting hypoxia inducible factor-1α/vascular endothelial growth factor/STAT3 pathway
por: Kong, Lingchun, et al.
Publicado: (2022)

Melatonin restricts the viability and angiogenesis of vascular endothelial cells by suppressing HIF-1α/ROS/VEGF
por: Cheng, Jiao, et al.
Publicado: (2019)

Lenticular cytoprotection. Part 1: The role of hypoxia inducible factors-1α and -2α and vascular endothelial growth factor in lens epithelial cell survival in hypoxia
por: Neelam, Sudha, et al.
Publicado: (2013)

Hypoxia initiates sirtuin1-mediated vascular endothelial growth factor activation in choroidal endothelial cells through hypoxia inducible factor–2α
por: Balaiya, Sankarathi, et al.
Publicado: (2012)

Hydrogen Sulfide Stimulates Ischemic Vascular Remodeling Through Nitric Oxide Synthase and Nitrite Reduction Activity Regulating Hypoxia‐Inducible Factor‐1α and Vascular Endothelial Growth Factor–Dependent Angiogenesis
por: Bir, Shyamal C., et al.
Publicado: (2012)

Aronia berry extract inhibits TNF-α-induced vascular endothelial inflammation through the regulation of STAT3
por: Iwashima, Tomomi, et al.
Publicado: (2019)

A Radicicol Derivative, KF58333, Inhibits Expression of Hypoxia‐inducible Factor‐1α and Vascular Endothelial Growth Factor, Angiogenesis and Growth of Human Breast Cancer Xenografts
por: Kurebayashi, Junichi, et al.
Publicado: (2001)

Two unrelated putative membrane-bound progestin receptors, progesterone membrane receptor component 1 (PGMRC1) and membrane progestin receptor (mPR) beta, are expressed in the rainbow trout oocyte and exhibit similar ovarian expression patterns
por: Mourot, Brigitte, et al.
Publicado: (2006)

The Regulation of Vascular Endothelial Growth Factor by Hypoxia and Prostaglandin F(2α) during Human Endometrial Repair
por: Maybin, Jacqueline A., et al.
Publicado: (2011)

Serum and molecular assessment of vascular endothelial growth factor (VEGF) and hypoxia-inducible factor 1α (HIF-1α) in canine mammary tumors
por: Moschetta, Marina G, et al.
Publicado: (2013)

S1PR1 induces metabolic reprogramming of ceramide in vascular endothelial cells, affecting hepatocellular carcinoma angiogenesis and progression
por: Wang, Xuehong, et al.
Publicado: (2022)

HIF-1α and HIF-2α induced angiogenesis in gastrointestinal vascular malformation and reversed by thalidomide
por: Feng, Nan, et al.
Publicado: (2016)

MicroRNA-126 regulates Hypoxia-Inducible Factor-1α which inhibited migration, proliferation, and angiogenesis in replicative endothelial senescence
por: Alique, Matilde, et al.
Publicado: (2019)

Hypoxia-Inducible Factor 1 alpha (HIF-1α)/Vascular Endothelial Growth Factor (VEGF) Pathway Participates in Angiogenesis of Myocardial Infarction in Muscone-Treated Mice: Preliminary Study
por: Du, Yingqiang, et al.
Publicado: (2018)

Hypoxia induced CCL28 promotes angiogenesis in lung adenocarcinoma by targeting CCR3 on endothelial cells
por: Huang, Guichun, et al.
Publicado: (2016)

Hypoxia-Inducible Factor 1-Α (HIF1α) and Vascular Endothelial Growth Factor-A (VEGF-A) Expression in De Novo AML Patients
por: Jabari, Mohammad, et al.
Publicado: (2019)

The endothelial αENaC contributes to vascular endothelial function in vivo
por: Tarjus, Antoine, et al.
Publicado: (2017)

Hypoxia promotes pulmonary vascular remodeling via HIF-1α to regulate mitochondrial dynamics
por: Chen, Xi, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_h5o4af2ac32184i1qttp2qeudn