Cargando…
Diabetic Ketoacidosis With Acute Metabolic Pancreatitis: Two Serious Cases
Hypertriglyceridemia is a rare cause of acute pancreatitis (AP), occupying approximately 7% of cases. The triad of acute pancreatitis, hypertriglyceridemia, and diabetes is a rare event, with a higher death rate. We describe two cases of severe acute metabolic pancreatitis discovered in diabetic ket...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817727/ https://www.ncbi.nlm.nih.gov/pubmed/35154963 http://dx.doi.org/10.7759/cureus.20987 |
_version_ | 1784645701113741312 |
---|---|
author | Rhmari Tlemçani, Fatima Zahra Delsa, Hanane Elamari, Saloua Rouibaa, Fedoua Chadli, Asma |
author_facet | Rhmari Tlemçani, Fatima Zahra Delsa, Hanane Elamari, Saloua Rouibaa, Fedoua Chadli, Asma |
author_sort | Rhmari Tlemçani, Fatima Zahra |
collection | PubMed |
description | Hypertriglyceridemia is a rare cause of acute pancreatitis (AP), occupying approximately 7% of cases. The triad of acute pancreatitis, hypertriglyceridemia, and diabetes is a rare event, with a higher death rate. We describe two cases of severe acute metabolic pancreatitis discovered in diabetic ketoacidosis. For both patients, all other causes of AP were excluded (including gallstones, hypercalcemia, drugs, and alcohol). A laboratory workup revealed elevated lipasemia (more than three times the normal) and hypertriglyceridemia. Abdominal computed tomography confirmed the diagnosis of severe acute pancreatitis. Fasting, fluid resuscitation, and insulin therapy were initiated in the intensive care unit with good clinical results and progressive improvement in metabolic disorders. |
format | Online Article Text |
id | pubmed-8817727 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-88177272022-02-10 Diabetic Ketoacidosis With Acute Metabolic Pancreatitis: Two Serious Cases Rhmari Tlemçani, Fatima Zahra Delsa, Hanane Elamari, Saloua Rouibaa, Fedoua Chadli, Asma Cureus Endocrinology/Diabetes/Metabolism Hypertriglyceridemia is a rare cause of acute pancreatitis (AP), occupying approximately 7% of cases. The triad of acute pancreatitis, hypertriglyceridemia, and diabetes is a rare event, with a higher death rate. We describe two cases of severe acute metabolic pancreatitis discovered in diabetic ketoacidosis. For both patients, all other causes of AP were excluded (including gallstones, hypercalcemia, drugs, and alcohol). A laboratory workup revealed elevated lipasemia (more than three times the normal) and hypertriglyceridemia. Abdominal computed tomography confirmed the diagnosis of severe acute pancreatitis. Fasting, fluid resuscitation, and insulin therapy were initiated in the intensive care unit with good clinical results and progressive improvement in metabolic disorders. Cureus 2022-01-06 /pmc/articles/PMC8817727/ /pubmed/35154963 http://dx.doi.org/10.7759/cureus.20987 Text en Copyright © 2022, Rhmari Tlemçani et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Endocrinology/Diabetes/Metabolism Rhmari Tlemçani, Fatima Zahra Delsa, Hanane Elamari, Saloua Rouibaa, Fedoua Chadli, Asma Diabetic Ketoacidosis With Acute Metabolic Pancreatitis: Two Serious Cases |
title | Diabetic Ketoacidosis With Acute Metabolic Pancreatitis: Two Serious Cases |
title_full | Diabetic Ketoacidosis With Acute Metabolic Pancreatitis: Two Serious Cases |
title_fullStr | Diabetic Ketoacidosis With Acute Metabolic Pancreatitis: Two Serious Cases |
title_full_unstemmed | Diabetic Ketoacidosis With Acute Metabolic Pancreatitis: Two Serious Cases |
title_short | Diabetic Ketoacidosis With Acute Metabolic Pancreatitis: Two Serious Cases |
title_sort | diabetic ketoacidosis with acute metabolic pancreatitis: two serious cases |
topic | Endocrinology/Diabetes/Metabolism |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817727/ https://www.ncbi.nlm.nih.gov/pubmed/35154963 http://dx.doi.org/10.7759/cureus.20987 |
work_keys_str_mv | AT rhmaritlemcanifatimazahra diabeticketoacidosiswithacutemetabolicpancreatitistwoseriouscases AT delsahanane diabeticketoacidosiswithacutemetabolicpancreatitistwoseriouscases AT elamarisaloua diabeticketoacidosiswithacutemetabolicpancreatitistwoseriouscases AT rouibaafedoua diabeticketoacidosiswithacutemetabolicpancreatitistwoseriouscases AT chadliasma diabeticketoacidosiswithacutemetabolicpancreatitistwoseriouscases |