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The ROS/GRK2/HIF-1α/NLRP3 Pathway Mediates Pyroptosis of Fibroblast-Like Synoviocytes and the Regulation of Monomer Derivatives of Paeoniflorin

Hypoxia is an important factor in the development of synovitis in rheumatoid arthritis (RA). The previous study of the research group found that monomeric derivatives of paeoniflorin (MDP) can alleviate joint inflammation in adjuvant-induced arthritis (AA) rats by inhibiting macrophage pyroptosis. T...

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Detalles Bibliográficos
Autores principales:	Hong, Zhongyang, Zhang, Xianzheng, Zhang, Tianjing, Hu, Ling, Liu, Ruijin, Wang, Pan, Wang, Han, Yu, Qianqian, Mei, Dan, Xue, Ziyang, Zhang, Feng, Zhang, Lingling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817856/ https://www.ncbi.nlm.nih.gov/pubmed/35132350 http://dx.doi.org/10.1155/2022/4566851

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