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Lipopolysaccharide acting via toll-like receptor 4 transactivates the TGF-β receptor in vascular smooth muscle cells

Toll-like receptors (TLRs) recognise pathogen‑associated molecular patterns, which allow the detection of microbial infection by host cells. Bacterial-derived toxin lipopolysaccharide activates TLR4 and leads to the activation of the Smad2 transcription factor. The phosphorylation of the Smad2 trans...

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Detalles Bibliográficos
Autores principales:	Afroz, Rizwana, Kumarapperuma, Hirushi, Nguyen, Quang V. N., Mohamed, Raafat, Little, Peter J., Kamato, Danielle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817999/ https://www.ncbi.nlm.nih.gov/pubmed/35122536 http://dx.doi.org/10.1007/s00018-022-04159-8

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