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Fish Allergy: Fishing for Novel Diagnostic and Therapeutic Options
Fish allergy is one of the most common food allergies. The currently recommended treatment commonly consists of avoiding all fish species. Recent literature suggests that these recommendations are overprotective for the majority of fish-allergic patients. This review summarizes recent findings and p...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818006/ https://www.ncbi.nlm.nih.gov/pubmed/32712803 http://dx.doi.org/10.1007/s12016-020-08806-5 |
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author | Dijkema, D. Emons, J. A. M. Van de Ven, A. A. J. M. Oude Elberink, J. N. G. |
author_facet | Dijkema, D. Emons, J. A. M. Van de Ven, A. A. J. M. Oude Elberink, J. N. G. |
author_sort | Dijkema, D. |
collection | PubMed |
description | Fish allergy is one of the most common food allergies. The currently recommended treatment commonly consists of avoiding all fish species. Recent literature suggests that these recommendations are overprotective for the majority of fish-allergic patients. This review summarizes recent findings and provides practical information regarding management of fish allergy in the individual patient. After precise history taking supported by additional specific IgE measurements and/or skin prick tests, fish-allergic patients can generally be categorized into the following clinical clusters: (A) poly-sensitized patients reacting to all fish species due to their sensitization to the panallergen β-parvalbumin, (B) mono-sensitized patients with selective reactions to individual fish species only, and (C) oligo-sensitized patients reacting to several specific fish. A number of allergens including parvalbumin, enolase, and aldolase can be involved. Depending on the specific cluster the patient belongs to, oral food challenges for one or more fish species can be performed with the aim to provide safe alternatives for consumption. This way, several alternative fish species can be identified for mono- and oligo-sensitized patients that can safely be consumed. Notably, even poly-sensitized patients generally tolerate fish species low in β-parvalbumin such as tuna and mackerel, particularly when processed. Taken together, allergological evaluation of patients with a documented fish allergy should be strongly considered, as it will allow the majority of patients to safely reintroduce one or more fish species. |
format | Online Article Text |
id | pubmed-8818006 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-88180062022-02-23 Fish Allergy: Fishing for Novel Diagnostic and Therapeutic Options Dijkema, D. Emons, J. A. M. Van de Ven, A. A. J. M. Oude Elberink, J. N. G. Clin Rev Allergy Immunol Article Fish allergy is one of the most common food allergies. The currently recommended treatment commonly consists of avoiding all fish species. Recent literature suggests that these recommendations are overprotective for the majority of fish-allergic patients. This review summarizes recent findings and provides practical information regarding management of fish allergy in the individual patient. After precise history taking supported by additional specific IgE measurements and/or skin prick tests, fish-allergic patients can generally be categorized into the following clinical clusters: (A) poly-sensitized patients reacting to all fish species due to their sensitization to the panallergen β-parvalbumin, (B) mono-sensitized patients with selective reactions to individual fish species only, and (C) oligo-sensitized patients reacting to several specific fish. A number of allergens including parvalbumin, enolase, and aldolase can be involved. Depending on the specific cluster the patient belongs to, oral food challenges for one or more fish species can be performed with the aim to provide safe alternatives for consumption. This way, several alternative fish species can be identified for mono- and oligo-sensitized patients that can safely be consumed. Notably, even poly-sensitized patients generally tolerate fish species low in β-parvalbumin such as tuna and mackerel, particularly when processed. Taken together, allergological evaluation of patients with a documented fish allergy should be strongly considered, as it will allow the majority of patients to safely reintroduce one or more fish species. Springer US 2020-07-25 2022 /pmc/articles/PMC8818006/ /pubmed/32712803 http://dx.doi.org/10.1007/s12016-020-08806-5 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Dijkema, D. Emons, J. A. M. Van de Ven, A. A. J. M. Oude Elberink, J. N. G. Fish Allergy: Fishing for Novel Diagnostic and Therapeutic Options |
title | Fish Allergy: Fishing for Novel Diagnostic and Therapeutic Options |
title_full | Fish Allergy: Fishing for Novel Diagnostic and Therapeutic Options |
title_fullStr | Fish Allergy: Fishing for Novel Diagnostic and Therapeutic Options |
title_full_unstemmed | Fish Allergy: Fishing for Novel Diagnostic and Therapeutic Options |
title_short | Fish Allergy: Fishing for Novel Diagnostic and Therapeutic Options |
title_sort | fish allergy: fishing for novel diagnostic and therapeutic options |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818006/ https://www.ncbi.nlm.nih.gov/pubmed/32712803 http://dx.doi.org/10.1007/s12016-020-08806-5 |
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