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Deciphering how naturally occurring sequence features impact the phase behaviors of disordered prion-like domains
Prion-like low complexity domains (PLCDs) have distinctive sequence grammars that determine their driving forces for phase separation. Here, we uncover the physicochemical underpinnings of how evolutionarily conserved compositional biases influence the phase behavior of PLCDs. We interpret our resul...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818026/ https://www.ncbi.nlm.nih.gov/pubmed/34931046 http://dx.doi.org/10.1038/s41557-021-00840-w |