Small Molecule Inhibitors that Disrupt the MTDH-SND1 Complex Suppress Breast Cancer Progression and Metastasis

Metastatic breast cancer is leading health burden worldwide. Previous studies have shown that Metadherin (MTDH) promotes breast cancer initiation, metastasis and therapy resistance; however, the therapeutic potential of targeting MTDH remains largely unexplored. Here, we used genetically modified mi...

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Detalles Bibliográficos
Autores principales: Shen, Minhong, Wei, Yong, Kim, Hahn, Wan, Liling, Jiang, Yi-Zhou, Hang, Xiang, Raba, Michael, Remiszewski, Stacy, Rowicki, Michelle, Wu, Cheng-Guo, Wu, Songyang, Zhang, Lanjing, Lu, Xin, Yuan, Min, Smith, Heath A., Zheng, Aiping, Bertino, Joseph, Jin, John F., Xing, Yongna, Shao, Zhi-Ming, Kang, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818087/
https://www.ncbi.nlm.nih.gov/pubmed/35121987
http://dx.doi.org/10.1038/s43018-021-00279-5

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