Pharmacological Disruption of the MTDH-SND1 Complex Enhances Tumor Antigen Presentation and Synergizes with Anti-PD-1 Therapy in Metastatic Breast Cancer

Despite the increased overall survival rates, curative options for metastatic breast cancer remain limited. We have previously shown that Metadherin (MTDH) is frequently overexpressed in poor prognosis breast cancer, where it promotes metastasis and therapy resistance through its interaction with St...

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Detalles Bibliográficos
Autores principales: Shen, Minhong, Smith, Heath A., Wei, Yong, Jiang, Yi-Zhou, Zhao, Sheng, Wang, Nicole, Rowicki, Michelle, Tang, Yong, Hang, Xiang, Wu, Songyang, Wan, Liling, Shao, Zhi-Ming, Kang, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818088/
https://www.ncbi.nlm.nih.gov/pubmed/35121988
http://dx.doi.org/10.1038/s43018-021-00280-y

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