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A dual role of HIF1α in regulating osteogenesis–angiogenesis coupling

OBJECTIVES: The hypoxia-inducible factor 1-α (HIF1α), a key molecule in mediating bone-vessel crosstalk, has been considered a promising target for treating osteoporosis caused by gonadal hormones. However, senile osteoporosis, with accumulated senescent cells in aged bone, has a distinct pathogenes...

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Detalles Bibliográficos
Autores principales:	Shao, Jingjing, Liu, Shibo, Zhang, Min, Chen, Shujiang, Gan, Shuaiqi, Chen, Chenfeng, Chen, Wenchuan, Li, Lei, Zhu, Zhimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818171/ https://www.ncbi.nlm.nih.gov/pubmed/35123567 http://dx.doi.org/10.1186/s13287-022-02742-1

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