BRAF-activated WT1 contributes to cancer growth and regulates autophagy and apoptosis in papillary thyroid carcinoma

BACKGROUND: Papillary thyroid carcinoma (PTC) is one of most prevalent malignant endocrine neoplasms, and it is associated with a high frequency of BRAF gene mutations, which lead to lymphatic metastasis and distant metastasis that promote tumor progression. The molecular mechanism of PTC and the ro...

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Detalles Bibliográficos
Autores principales: Chen, Xing, Lin, Shan, Lin, Ying, Wu, Songsong, Zhuo, Minling, Zhang, Ailong, Zheng, Junjie, You, Zhenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818187/
https://www.ncbi.nlm.nih.gov/pubmed/35123502
http://dx.doi.org/10.1186/s12967-022-03260-7

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