Elevated RIF1 participates in the epigenetic abnormalities of zygotes by regulating histone modifications on MuERV-L in obese mice

BACKGROUND: Maternal obesity impairs embryonic developmental potential and significantly increases the risks of metabolic disorders in offspring. However, the epigenetic transmission mechanism of maternal metabolic abnormalities is still poorly understood. METHODS: We established an obesity model in...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Jiliang, Ru, Gaizhen, Sun, Jiajia, Sun, Luying, Li, Zhiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818203/
https://www.ncbi.nlm.nih.gov/pubmed/35123389
http://dx.doi.org/10.1186/s10020-022-00446-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818203/
https://www.ncbi.nlm.nih.gov/pubmed/35123389
http://dx.doi.org/10.1186/s10020-022-00446-z

Ejemplares similares