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Accumulation of acetaldehyde in aldh2.1(−/−) zebrafish causes increased retinal angiogenesis and impaired glucose metabolism

Reactive carbonyl species (RCS) are spontaneously formed in the metabolism and modify and impair the function of DNA, proteins and lipids leading to several organ complications. In zebrafish, knockout of the RCS detoxifying enzymes glyoxalase 1 (Glo 1), aldehyde dehydrogenase 3a1 (Aldh3a1) and aldo-...

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Detalles Bibliográficos
Autores principales:	Wohlfart, David Philipp, Lou, Bowen, Middel, Chiara Simone, Morgenstern, Jakob, Fleming, Thomas, Sticht, Carsten, Hausser, Ingrid, Hell, Rüdiger, Hammes, Hans-Peter, Szendrödi, Julia, Nawroth, Peter Paul, Kroll, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818574/ https://www.ncbi.nlm.nih.gov/pubmed/35114580 http://dx.doi.org/10.1016/j.redox.2022.102249

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