Flow-induced endothelial mitochondrial remodeling mitigates mitochondrial reactive oxygen species production and promotes mitochondrial DNA integrity in a p53-dependent manner

Tumor suppressor p53 plays a pivotal role in orchestrating mitochondrial remodeling by regulating their content, fusion/fission processes, and intracellular signaling molecules that are associated with mitophagy and apoptosis pathways. In order to determine a molecular mechanism underlying flow-medi...

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Detalles Bibliográficos
Autores principales: Shin, Junchul, Hong, Soon-Gook, Choi, Soo Young, Rath, Meghan E., Saredy, Jason, Jovin, Daniel G., Sayoc, Jacqueline, Park, Hye-Sang, Eguchi, Satoru, Rizzo, Victor, Scalia, Rosario, Wang, Hong, Houser, Steven R., Park, Joon-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818582/
https://www.ncbi.nlm.nih.gov/pubmed/35121402
http://dx.doi.org/10.1016/j.redox.2022.102252

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