Activation of Akt–mTORC1 signalling reverts cancer‐dependent muscle wasting

BACKGROUND: Cancer‐related muscle wasting occurs in most cancer patients. An important regulator of adult muscle mass and function is the Akt–mTORC1 pathway. While Akt–mTORC1 signalling is important for adult muscle homeostasis, it is also a major target of numerous cancer treatments. Which role Akt...

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Detalles Bibliográficos
Autores principales: Geremia, Alessia, Sartori, Roberta, Baraldo, Martina, Nogara, Leonardo, Balmaceda, Valeria, Dumitras, Georgia Ana, Ciciliot, Stefano, Scalabrin, Marco, Nolte, Hendrik, Blaauw, Bert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles: Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818597/
https://www.ncbi.nlm.nih.gov/pubmed/34741441
http://dx.doi.org/10.1002/jcsm.12854

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