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Sepsis induces interleukin 6, gp130/JAK2/STAT3, and muscle wasting

BACKGROUND: Sepsis and inflammation can cause intensive care unit‐acquired weakness (ICUAW). Increased interleukin‐6 (IL‐6) plasma levels are a risk factor for ICUAW. IL‐6 signalling involves the glycoprotein 130 (gp130) receptor and the JAK/STAT‐pathway, but its role in sepsis‐induced muscle wastin...

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Detalles Bibliográficos
Autores principales:	Zanders, Lukas, Kny, Melanie, Hahn, Alexander, Schmidt, Sibylle, Wundersitz, Sebastian, Todiras, Mihail, Lahmann, Ines, Bandyopadhyay, Arnab, Wollersheim, Tobias, Kaderali, Lars, Luft, Friedrich C., Birchmeier, Carmen, Weber‐Carstens, Steffen, Fielitz, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles: Basic Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818599/ https://www.ncbi.nlm.nih.gov/pubmed/34821076 http://dx.doi.org/10.1002/jcsm.12867

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