Cargando…

Progressive Retinal and Optic Nerve Damage in a Mouse Model of Spontaneous Opticospinal Encephalomyelitis

Neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein-antibody-associated disease (MOGAD) are antibody mediated CNS disorders mostly affecting the optic nerve and spinal cord with potential severe impact on the visual pathway. Here, we investigated inflammation and d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Petrikowski, Laura, Reinehr, Sabrina, Haupeltshofer, Steffen, Deppe, Leonie, Graz, Florian, Kleiter, Ingo, Dick, H. Burkhard, Gold, Ralf, Faissner, Simon, Joachim, Stephanie C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818777/ https://www.ncbi.nlm.nih.gov/pubmed/35140707 http://dx.doi.org/10.3389/fimmu.2021.759389

Ejemplares similares

Prophylactic Glatiramer Acetate Treatment Positively Attenuates Spontaneous Opticospinal Encephalomyelitis
por: Koc, Ümmügülsüm, et al.
Publicado: (2023)

Laquinimod protects the optic nerve and retina in an experimental autoimmune encephalomyelitis model
por: Wilmes, Anna T., et al.
Publicado: (2018)

Clozapine Regulates Microglia and Is Effective in Chronic Experimental Autoimmune Encephalomyelitis
por: Ceylan, Ulaş, et al.
Publicado: (2021)

Fingolimod for Irradiation-Induced Neurodegeneration
por: Metzdorf, Judith, et al.
Publicado: (2019)

Simultaneous Complement Response via Lectin Pathway in Retina and Optic Nerve in an Experimental Autoimmune Glaucoma Model
por: Reinehr, Sabrina, et al.
Publicado: (2016)

Aquaporin-4 antibodies in patients treated with natalizumab for suspected MS
por: Gahlen, Anna, et al.
Publicado: (2017)

Early remodelling of the extracellular matrix proteins tenascin‐C and phosphacan in retina and optic nerve of an experimental autoimmune glaucoma model
por: Reinehr, Sabrina, et al.
Publicado: (2016)

Heat Shock Protein 27 Injection Leads to Caspase Activation in the Visual Pathway and Retinal T-Cell Response
por: Grotegut, Pia, et al.
Publicado: (2021)

Amphiphysin-positive paraneoplastic myelitis and stiff-person syndrome
por: Faissner, Simon, et al.
Publicado: (2016)

S100B immunization triggers NFκB and complement activation in an autoimmune glaucoma model
por: Reinehr, Sabrina, et al.
Publicado: (2018)

Transfer of the Experimental Autoimmune Glaucoma Model from Rats to Mice—New Options to Study Glaucoma Disease
por: Reinehr, Sabrina, et al.
Publicado: (2019)

Loss of retinal ganglion cells in a new genetic mouse model for primary open‐angle glaucoma
por: Reinehr, Sabrina, et al.
Publicado: (2019)

Neuromyelitis optica spectrum disorders with non opticospinal manifestations as initial symptoms: a long-term observational study
por: Li, Rui, et al.
Publicado: (2021)

Preservation of optic nerve structure by complement inhibition in experimental glaucoma
por: Gassel, Caroline J., et al.
Publicado: (2020)

Correction to: Preservation of optic nerve structure by complement inhibition in experimental glaucoma
por: Gassel, Caroline J., et al.
Publicado: (2021)

Microglia Activation in Retinal Ischemia Triggers Cytokine and Toll-Like Receptor Response
por: Wagner, Natalie, et al.
Publicado: (2020)

Optic Nerve Degeneration after Retinal Ischemia/Reperfusion in a Rodent Model
por: Renner, Marina, et al.
Publicado: (2017)

Intravitreal Therapy Against the Complement Factor C5 Prevents Retinal Degeneration in an Experimental Autoimmune Glaucoma Model
por: Reinehr, Sabrina, et al.
Publicado: (2019)

Proteomic Analysis of Retinal Tissue in an S100B Autoimmune Glaucoma Model
por: Reinehr, Sabrina, et al.
Publicado: (2021)

Does MOG Ig-positive AQP4-seronegative opticospinal inflammatory disease justify a diagnosis of NMO spectrum disorder?
por: Zamvil, Scott S., et al.
Publicado: (2015)

HSP27 induced glaucomatous damage in mice of young and advanced age
por: Erb, Clivia, et al.
Publicado: (2023)

Protective effects on the retina after ranibizumab treatment in an ischemia model
por: Joachim, Stephanie C., et al.
Publicado: (2017)

1,25-OH(2) vitamin D(3) and AKT-inhibition increase glucocorticoid induced apoptosis in a model of T-cell acute lymphoblastic leukemia (ALL)
por: Pistor, Maximilian, et al.
Publicado: (2018)

Loss of the Extracellular Matrix Molecule Tenascin-C Leads to Absence of Reactive Gliosis and Promotes Anti-inflammatory Cytokine Expression in an Autoimmune Glaucoma Mouse Model
por: Wiemann, Susanne, et al.
Publicado: (2020)

Analysis of Neurogenesis during Experimental Autoimmune Encephalomyelitis Reveals Pitfalls of Bioluminescence Imaging
por: Ayzenberg, Ilya, et al.
Publicado: (2015)

Gaze palsy, hypogeusia and a probable association with miscarriage of pregnancy - the expanding clinical spectrum of non-opticospinal neuromyelitis optica spectrum disorders: a case report
por: Chang, Thashi, et al.
Publicado: (2015)

Synapse and Receptor Alterations in Two Different S100B-Induced Glaucoma-Like Models
por: Benning, Lara, et al.
Publicado: (2020)

Hypoxic Processes Induce Complement Activation via Classical Pathway in Porcine Neuroretinas
por: Mueller-Buehl, Ana M., et al.
Publicado: (2021)

Induction of Regulatory Properties in the Intestinal Immune System by Dimethyl Fumarate in Lewis Rat Experimental Autoimmune Neuritis
por: Pitarokoili, Kalliopi, et al.
Publicado: (2019)

Inflammatory demyelination induces glia alterations and ganglion cell loss in the retina of an experimental autoimmune encephalomyelitis model
por: Horstmann, Lioba, et al.
Publicado: (2013)

Novel Porcine Retina Cultivation Techniques Provide Improved Photoreceptor Preservation
por: Wagner, Natalie, et al.
Publicado: (2020)

Cytokine and Complement Response in the Glaucomatous βB1-CTGF Mouse Model
por: Reinehr, Sabrina, et al.
Publicado: (2021)

Inner Retinal Layer Changes Reflect Changes in Ambulation Score in Patients with Primary Progressive Multiple Sclerosis
por: Gernert, Jonathan A., et al.
Publicado: (2023)

Progressive multiple sclerosis: latest therapeutic developments and future directions
por: Faissner, Simon, et al.
Publicado: (2019)

Efficacy and Safety of Multiple Sclerosis Drugs Approved Since 2018 and Future Developments
por: Faissner, Simon, et al.
Publicado: (2022)

Tenascins in Retinal and Optic Nerve Neurodegeneration
por: Reinhard, Jacqueline, et al.
Publicado: (2017)

Immune response against ocular tissues after immunization with optic nerve antigens in a model of autoimmune glaucoma
por: Joachim, Stephanie C., et al.
Publicado: (2013)

Heat Shock Protein Upregulation Supplemental to Complex mRNA Alterations in Autoimmune Glaucoma
por: Reinehr, Sabrina, et al.
Publicado: (2022)

Activation of Apoptosis in a βB1-CTGF Transgenic Mouse Model
por: Weiss, Maximilian, et al.
Publicado: (2021)

Enhanced glaucomatous damage accompanied by glial response in a new multifactorial mouse model
por: Reinehr, Sabrina, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3078b05jrnrlvr9v5aifre56fu