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Autocrine/Paracrine Loop Between SCF(+)/c-Kit(+) Mast Cells Promotes Cutaneous Melanoma Progression
c-Kit, or mast/stem cell growth factor receptor Kit, is a tyrosine kinase receptor structurally analogous to the colony-stimulating factor-1 (CSF-1) and platelet-derived growth factor (PDGF) CSF-1/PDGF receptor Tyr-subfamily. It binds the cytokine KITLG/SCF to regulate cell survival and proliferatio...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818866/ https://www.ncbi.nlm.nih.gov/pubmed/35140718 http://dx.doi.org/10.3389/fimmu.2022.794974 |