Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer’s Disease

Animal models of disease are valuable resources for investigating pathogenic mechanisms and potential therapeutic interventions. However, for complex disorders such as Alzheimer’s disease (AD), the generation and availability of innumerous distinct animal models present unique challenges to AD resea...

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Detalles Bibliográficos
Autores principales: Javonillo, Dominic I., Tran, Kristine M., Phan, Jimmy, Hingco, Edna, Kramár, Enikö A., da Cunha, Celia, Forner, Stefania, Kawauchi, Shimako, Milinkeviciute, Giedre, Gomez-Arboledas, Angela, Neumann, Jonathan, Banh, Crystal E., Huynh, Michelle, Matheos, Dina P., Rezaie, Narges, Alcantara, Joshua A., Mortazavi, Ali, Wood, Marcelo A., Tenner, Andrea J., MacGregor, Grant R., Green, Kim N., LaFerla, Frank M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818877/
https://www.ncbi.nlm.nih.gov/pubmed/35140584
http://dx.doi.org/10.3389/fnins.2021.785276

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