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The Multi-Omics Analysis of Key Genes Regulating EGFR-TKI Resistance, Immune Infiltration, SCLC Transformation in EGFR-Mutant NSCLC

BACKGROUND: Lung cancer is a high-risk malignancy worldwide. The harboring of epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) makes EGFR-tyrosine kinase inhibitor (EGFR-TKI) an attractive therapeutic option. However, patients usually suffer the primary and sec...

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Detalles Bibliográficos
Autores principales: Wang, Zhi, Zhang, Lingling, Xu, Wenwen, Li, Jie, Liu, Yi, Zeng, Xiaozhu, Zhong, Maoxi, Zhu, Yuxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818984/
https://www.ncbi.nlm.nih.gov/pubmed/35140497
http://dx.doi.org/10.2147/JIR.S341001

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