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The PDE4 Inhibitor Tanimilast Blunts Proinflammatory Dendritic Cell Activation by SARS-CoV-2 ssRNAs

Phosphodiesterase 4 (PDE4) inhibitors are immunomodulatory drugs approved to treat diseases associated with chronic inflammatory conditions, such as COPD, psoriasis and atopic dermatitis. Tanimilast (international non-proprietary name of CHF6001) is a novel, potent and selective inhaled PDE4 inhibit...

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Detalles Bibliográficos
Autores principales:	Nguyen, Hoang Oanh, Schioppa, Tiziana, Tiberio, Laura, Facchinetti, Fabrizio, Villetti, Gino, Civelli, Maurizio, Del Prete, Annalisa, Sozio, Francesca, Gaudenzi, Carolina, Passari, Mauro, Barbazza, Ilaria, Sozzani, Silvano, Salvi, Valentina, Bosisio, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818995/ https://www.ncbi.nlm.nih.gov/pubmed/35140709 http://dx.doi.org/10.3389/fimmu.2021.797390

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