IKKβ signaling mediates metabolic changes in the hypothalamus of a Huntington disease mouse model

Huntington disease (HD) is a neurodegenerative disorder caused by a CAG repeat expansion in the huntingtin (HTT) gene. Metabolic changes are associated with HD progression, but underlying mechanisms are not fully known. As the IKKβ/NF-κB pathway is an essential regulator of metabolism, we investigat...

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Detalles Bibliográficos
Autores principales: Soylu-Kucharz, Rana, Khoshnan, Ali, Petersén, Åsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819015/
https://www.ncbi.nlm.nih.gov/pubmed/35146388
http://dx.doi.org/10.1016/j.isci.2022.103771

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819015/
https://www.ncbi.nlm.nih.gov/pubmed/35146388
http://dx.doi.org/10.1016/j.isci.2022.103771

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