CRISPR-Cas9‒Based Genomic Engineering in Keratinocytes: From Technology to Application

CRISPR-Cas9 is the most straightforward genome-editing tool to date. However, its implementation across disciplines is hampered by variable genome-editing efficiencies, reduced cell viability, and low success rates in obtaining clonal cell lines. This review aims to recognize all CRISPR-Cas9‒related...

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Detalles Bibliográficos
Autores principales: Smits, Jos P.H., Meesters, Luca D., Maste, Berber G.W., Zhou, Huiqing, Zeeuwen, Patrick L.J.M., van den Bogaard, Ellen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819031/
https://www.ncbi.nlm.nih.gov/pubmed/35146483
http://dx.doi.org/10.1016/j.xjidi.2021.100082

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