The Rho guanine nucleotide exchange factor PLEKHG1 is activated by interaction with and phosphorylation by Src family kinase member FYN

Rho family small GTPases (Rho) regulate various cell motility processes by spatiotemporally controlling the actin cytoskeleton. Some Rho-specific guanine nucleotide exchange factors (RhoGEFs) are regulated via tyrosine phosphorylation by Src family tyrosine kinase (SFK). We also previously reported...

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Detalles Bibliográficos
Autores principales: Nakano, Shun, Nishikawa, Masashi, Kobayashi, Tomoyo, Harlin, Eka Wahyuni, Ito, Takuya, Sato, Katsuya, Sugiyama, Tsuyoshi, Yamakawa, Hisashi, Nagase, Takahiro, Ueda, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819033/
https://www.ncbi.nlm.nih.gov/pubmed/35031323
http://dx.doi.org/10.1016/j.jbc.2022.101579

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