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Rational Design and Synthesis of 3-Morpholine Linked Aromatic-Imino-1H-Indoles as Novel Kv1.5 Channel Inhibitors Sharing Vasodilation Effects

Atrial fibrillation (AF) is the most common clinical sustained arrhythmia; clinical therapeutic drugs have low atrial selectivity and might cause more severe ventricle arrhythmias while stopping AF. As an anti-AF drug target with high selectivity on the atrial muscle cells, the undetermined crystal...

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Detalles Bibliográficos
Autores principales:	Qin, Wei, Li, Yi-Heng, Tong, Jing, Wu, Jie, Zhao, Dong, Li, Hui-Jin, Xing, Lu, He, Chun-Xia, Zhou, Xin, Li, Peng-Quan, Meng, Ge, Wu, Shao-Ping, Cao, Hui-Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819089/ https://www.ncbi.nlm.nih.gov/pubmed/35141279 http://dx.doi.org/10.3389/fmolb.2021.805594

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