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TCOF1 coordinates oncogenic activation and rRNA production and promotes tumorigenesis in HCC

Treacle ribosome biogenesis factor 1 (TCOF1) is a nucleolar factor that regulates ribosomal DNA (rDNA) transcription in the nucleolus. TCOF1 has been previously reported to be implicated in Treacher Collins–Franceschetti syndrome (TCS), a congenital disorder of craniofacial development. Except TCS,...

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Detalles Bibliográficos
Autores principales: Wu, Chaoshen, Xia, Dian, Wang, Dian, Wang, Shu, Sun, Zhaoran, Xu, Bihuai, Zhang, Daoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819287/
https://www.ncbi.nlm.nih.gov/pubmed/34904330
http://dx.doi.org/10.1111/cas.15242