TAS‐116 (pimitespib), a heat shock protein 90 inhibitor, shows efficacy in preclinical models of adult T‐cell leukemia

Adult T‐cell leukemia/lymphoma (ATL) is a highly chemoresistant malignancy of peripheral T lymphocytes caused by human T‐cell leukemia virus type 1 infection, for which there is an urgent need for more effective therapeutic options. The molecular chaperone heat shock protein 90 (HSP90) plays a cruci...

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Detalles Bibliográficos
Autores principales: Ikebe, Emi, Shimosaki, Shunsuke, Hasegawa, Hiroo, Iha, Hidekatsu, Tsukamoto, Yoshiyuki, Wang, Yu, Sasaki, Daisuke, Imaizumi, Yoshitaka, Miyazaki, Yasushi, Yanagihara, Katsunori, Hamaguchi, Isao, Morishita, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819293/
https://www.ncbi.nlm.nih.gov/pubmed/34794206
http://dx.doi.org/10.1111/cas.15204

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819293/
https://www.ncbi.nlm.nih.gov/pubmed/34794206
http://dx.doi.org/10.1111/cas.15204

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