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E239K mutation abolishes the suppressive effects of lysine‐specific demethylase 1 on migration and invasion of MCF7 cells

Lysine‐specific demethylase 1 (LSD1) is an important histone demethylase that mediates epithelial to mesenchymal transition (EMT). The E239K mutation of LSD1 was identified in a luminal breast cancer patient from the COSMIC Breast Cancer dataset. To investigate the functional effects of the E239K mu...

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Detalles Bibliográficos
Autores principales:	Zhang, Yu, Wu, Tong, Zhao, Bo, Liu, Ziyu, Qian, Rui, Zhang, Jing, Shi, Yueru, Wan, Youzhong, Li, Zhe, Hu, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819338/ https://www.ncbi.nlm.nih.gov/pubmed/34839571 http://dx.doi.org/10.1111/cas.15220

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