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PDRG1 promotes the proliferation and migration of GBM cells by the MEK/ERK/CD44 pathway

P53 and DNA damage‐regulated gene1 (PDRG1) is overexpressed in diverse carcinomas. Here, we discover that PDRG1 is overexpressed in glioblastoma multiforme (GBM). However, the clinical significance, biological role, and underlying molecular mechanisms of PDRG1 in GBM remain unclear. PDRG1 was aberra...

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Detalles Bibliográficos
Autores principales: Sun, Jinmin, Xu, Yixin, Liu, Jia, Cui, Huiyue, Cao, Haowei, Ren, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819344/
https://www.ncbi.nlm.nih.gov/pubmed/34812552
http://dx.doi.org/10.1111/cas.15214

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