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Sigma 1 Receptor Contributes to Astrocyte-Mediated Retinal Ganglion Cell Protection

PURPOSE: Sigma 1 receptor (S1R) is expressed in retinal ganglion cells (RGCs) and astrocytes, and its activation is neuroprotective. We evaluated the contribution of S1R within optic nerve head astrocytes (ONHAs) to growth and survival of RGCs in vitro. METHODS: Wild-type (WT) RGCs and WT or S1R kno...

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Detalles Bibliográficos
Autores principales:	Zhao, Jing, Gonsalvez, Graydon B., Mysona, Barbara A., Smith, Sylvia B., Bollinger, Kathryn E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2022
Materias:	Retinal Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819349/ https://www.ncbi.nlm.nih.gov/pubmed/35103752 http://dx.doi.org/10.1167/iovs.63.2.1

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