PD-L1(+)CD8(+) T cells enrichment in lung cancer exerted regulatory function and tumor-promoting tolerance

Immunotherapy targeting checkpoint blockade to rescue T cells from exhaustion has become an essential therapeutic strategy in treating cancers. Till now, little is known about the PD-L1 graphic pattern and characteristics in CD8(+) T cells. We combined cytometry by time-of-flight (CyTOF) and imaging...

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Detalles Bibliográficos
Autores principales: Zheng, Yingxia, Han, Li, Chen, Zheyi, Li, Yiyang, Zhou, Bingqian, Hu, Rui, Chen, Shiyu, Xiao, Haibo, Ma, Yanhui, Xie, Guohua, Yang, Junyao, Ding, Xianting, Shen, Lisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819393/
https://www.ncbi.nlm.nih.gov/pubmed/35146396
http://dx.doi.org/10.1016/j.isci.2022.103785

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