Cargando…

Periodontal Ligament Stem Cell-Derived Small Extracellular Vesicles Embedded in Matrigel Enhance Bone Repair Through the Adenosine Receptor Signaling Pathway

PURPOSE: Small extracellular vesicles (sEVs) are natural biocarriers for biomolecule transfer between cells and promising therapeutic strategies for bone defect repair. In this study, human periodontal ligament stem cell (PDLSC)-derived sEVs (P-EVs) were immobilized in Matrigel to establish a topica...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Bingjiao, Chen, Qingqing, Zhao, Liru, Mao, Jiaqi, Huang, Wei, Han, Xinxin, Liu, Yuehua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819539/ https://www.ncbi.nlm.nih.gov/pubmed/35140462 http://dx.doi.org/10.2147/IJN.S346755

Ejemplares similares

Rab27a-mediated extracellular vesicle secretion contributes to osteogenesis in periodontal ligament-bone niche communication
por: Lu, Yun, et al.
Publicado: (2023)

Roles of extracellular adenosine triphosphate on the functions of periodontal ligament cells
por: Kyawsoewin, Maythwe, et al.
Publicado: (2023)

Extracellular Vesicles for Dental Pulp and Periodontal Regeneration
por: Lai, Hongbin, et al.
Publicado: (2023)

From MEFs to Matrigel 3: Passaging hESCs from Matrigel onto Matrigel
por: Zhang, Jin, et al.
Publicado: (2008)

Transient Retention of Photoreceptor Outer Segments in Matrigel-Embedded Retinal Organoids
por: Berber, Patricia, et al.
Publicado: (2022)

Tissue extracellular matrix hydrogels as alternatives to Matrigel for culturing gastrointestinal organoids
por: Kim, Suran, et al.
Publicado: (2022)

Silk–Inorganic Nanoparticle Hybrid Hydrogel as an Injectable Bone Repairing Biomaterial
por: Sun, Liangyan, et al.
Publicado: (2023)

The deficits of matrigel plug assay
por: Kurt, Yasemin Gülcan, et al.
Publicado: (2014)

Bone repair by periodontal ligament stem cellseeded nanohydroxyapatite-chitosan scaffold
por: Ge, Shaohua, et al.
Publicado: (2012)

Improved phosphoproteomic analysis for phosphosignaling and active-kinome profiling in Matrigel-embedded spheroids and patient-derived organoids
por: Abe, Yuichi, et al.
Publicado: (2018)

Extracellular matrix bioink boosts stemness and facilitates transplantation of intestinal organoids as a biosafe Matrigel alternative
por: Xu, Zi‐Yan, et al.
Publicado: (2022)

Matrigel patterning reflects multicellular contractility
por: Méhes, Előd, et al.
Publicado: (2019)

Towards organoid culture without Matrigel
por: Kozlowski, Mark T., et al.
Publicado: (2021)

Bioprinting of Matrigel Scaffolds for Cancer Research
por: De Stefano, Paola, et al.
Publicado: (2021)

High-Fat Diet-Induced Mitochondrial Dysfunction Promotes Genioglossus Injury – A Potential Mechanism for Obstructive Sleep Apnea with Obesity
por: Chen, Qingqing, et al.
Publicado: (2021)

Optimization of extracellular matrix for primary human hepatocyte cultures using mixed collagen-Matrigel matrices
por: Seidemann, Lena, et al.
Publicado: (2023)

Matrigel is required for efficient differentiation of isolated, stem cell-derived otic vesicles into inner ear organoids
por: Hocevar, Sarah Emily, et al.
Publicado: (2021)

Nanotherapy for bone repair: milk-derived small extracellular vesicles delivery of icariin
por: Yu, Xinxin, et al.
Publicado: (2023)

A novel role in skeletal segment regeneration of extracellular vesicles released from periodontal-ligament stem cells
por: Diomede, Francesca, et al.
Publicado: (2018)

Lipopolysaccharide-Preconditioned Periodontal Ligament Stem Cells Induce M1 Polarization of Macrophages through Extracellular Vesicles
por: Kang, Hyejong, et al.
Publicado: (2018)

Engineered Extracellular Vesicles From Human Periodontal-Ligament Stem Cells Increase VEGF/VEGFR2 Expression During Bone Regeneration
por: Pizzicannella, Jacopo, et al.
Publicado: (2019)

Extracellular Matrix Induces Periodontal Ligament Reconstruction In Vivo
por: Nakamura, Naoko, et al.
Publicado: (2019)

Extracellular vesicles in bone and periodontal regeneration: current and potential therapeutic applications
por: Gholami, Leila, et al.
Publicado: (2021)

Extracellular Vesicles of Human Periodontal Ligament Stem Cells Contain MicroRNAs Associated to Proto-Oncogenes: Implications in Cytokinesis
por: Chiricosta, Luigi, et al.
Publicado: (2020)

Addendum: Engineered extracellular vesicles from human periodontal-ligament stem cells increase VEGF/VEGFR2 expression during bone regeneration
por: Pizzicannella, Jacopo, et al.
Publicado: (2023)

Functional model of rat thyroid follicles cultured in Matrigel
por: Khoruzhenko, Antonina, et al.
Publicado: (2021)

Roles of extracellular vesicles in periodontal homeostasis and their therapeutic potential
por: Deng, Dao-Kun, et al.
Publicado: (2022)

The role of extracellular vesicles in periodontitis: pathogenesis, diagnosis, and therapy
por: Cai, Rong, et al.
Publicado: (2023)

Cell-derived extracellular vesicles and membranes for tissue repair
por: Ding, Yuan, et al.
Publicado: (2021)

Inhibitory effects of 17β-estradiol or a resveratrol dimer on hypoxia-inducible factor-1α in genioglossus myoblasts: Involvement of ERα and its downstream p38 MAPK pathways
por: Li, Yuanyuan, et al.
Publicado: (2017)

Vertical Control of a Severe Hyperdivergent Skeletal Class II Malocclusion with Steep Posterior Occlusal Plane in a Camouflage Case
por: Lu, Yun, et al.
Publicado: (2022)

Mesenchymal Stem Cell-Derived Extracellular Vesicles in Tendon and Ligament Repair—A Systematic Review of In Vivo Studies
por: Lu, Victor, et al.
Publicado: (2021)

Matrigel scaffold combined with Ad-hBMP7-transfected chondrocytes improves the repair of rabbit cartilage defect
por: Xia, Xiaopeng, et al.
Publicado: (2017)

Curcumin-primed periodontal ligament stem cells-derived extracellular vesicles improve osteogenic ability through the Wnt/β-catenin pathway
por: Lan, Qian, et al.
Publicado: (2023)

Method for improved integrity of RNA isolated from Matrigel cultures
por: Da Silva, Lais, et al.
Publicado: (2020)

Matrigel® enhances 3T3-L1 cell differentiation
por: Josan, Chitmandeep, et al.
Publicado: (2021)

In-Depth Comparison of Matrigel Dissolving Methods on Proteomic Profiling of Organoids
por: Wang, Man, et al.
Publicado: (2021)

Extracellular Matrix Membrane Induces Cementoblastic/Osteogenic Properties of Human Periodontal Ligament Stem Cells
por: Wang, Yuanyuan, et al.
Publicado: (2018)

Harnessing extracellular vesicles to direct endochondral repair of large bone defects
por: Ferreira, E., et al.
Publicado: (2018)

Mesenchymal Stem Cell-Derived Extracellular Vesicles for Bone Defect Repair
por: Wang, Dongxue, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_46eqnrfs3rvl0oem31uiob5ngi