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Limonin, an AMPK Activator, Inhibits Hepatic Lipid Accumulation in High Fat Diet Fed Mice
NAFLD is the most prevalent liver disease in human history. The treatment is still limited yet. In the current study, we reported that limonin inhibited hepatic lipid accumulation and fatty acid synthesis in HFD fed mice. Using AMPK inhibitor and AMPK deficient C. elegans, we revealed the effect was...
Autores principales: | Wang, Si-wei, Lan, Tian, Chen, Hang-fei, Sheng, Hao, Xu, Chun-yi, Xu, Li-feng, Zheng, Fang, Zhang, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819594/ https://www.ncbi.nlm.nih.gov/pubmed/35140621 http://dx.doi.org/10.3389/fphar.2022.833705 |
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