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Pharmacokinetics, Pharmacodynamics, Safety and Immunogenicity of CMAB807, a New Denosumab Biosimilar, in Healthy Chinese Subjects

Objective: Pharmacokinetics (PK), pharmacodynamics (PD), safety and immunogenicity studies were conducted to evaluate the bioequivalence of CMAB807, a biosimilar to denosumab (Prolia(®)), which is the only approved RANKL inhibitor for the treatment of osteoporosis. Methods: In this randomized, doubl...

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Detalles Bibliográficos
Autores principales:	Chen, Hanjing, Chen, Weili, Yuan, Fei, Guo, Qingcheng, Zhang, Xunmin, Wang, Chenguang, Li, Xuening
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819684/ https://www.ncbi.nlm.nih.gov/pubmed/35140619 http://dx.doi.org/10.3389/fphar.2022.821944

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