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Reconstitution and use of highly active human CDK1:Cyclin‐B:CKS1 complexes

As dividing cells transition into mitosis, hundreds of proteins are phosphorylated by a complex of cyclin‐dependent kinase 1 (CDK1) and Cyclin‐B, often at multiple sites. CDK1:Cyclin‐B phosphorylation patterns alter conformations, interaction partners, and enzymatic activities of target proteins and...

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Detalles Bibliográficos
Autores principales:	Huis in 't Veld, Pim J., Wohlgemuth, Sabine, Koerner, Carolin, Müller, Franziska, Janning, Petra, Musacchio, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2021
Materias:	Methods and Applications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819839/ https://www.ncbi.nlm.nih.gov/pubmed/34791727 http://dx.doi.org/10.1002/pro.4233

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