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Intravenous lidocaine in spine surgery: A meta-analysis of randomized controlled trials
BACKGROUND: This study aimed to evaluate the role of intravenous lidocaine as a supplemental pain control modality in patients undergoing spine surgery. METHODS: We conducted a meta-analysis of randomized controlled trials (RCTs) involving the use of supplemental intravenous lidocaine in spine surge...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819964/ https://www.ncbi.nlm.nih.gov/pubmed/35141644 http://dx.doi.org/10.1016/j.xnsj.2021.100079 |
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author | Haratian, Aryan Musa, Arif Field, Ryan Farhan, Saif Bennett, Collin Cooke, Christopher Patel, Rakesh D. Aleem, Ilyas S. Eichler, Martin C. Rajalingam, Karan Lee, Carlin Bederman, Samuel |
author_facet | Haratian, Aryan Musa, Arif Field, Ryan Farhan, Saif Bennett, Collin Cooke, Christopher Patel, Rakesh D. Aleem, Ilyas S. Eichler, Martin C. Rajalingam, Karan Lee, Carlin Bederman, Samuel |
author_sort | Haratian, Aryan |
collection | PubMed |
description | BACKGROUND: This study aimed to evaluate the role of intravenous lidocaine as a supplemental pain control modality in patients undergoing spine surgery. METHODS: We conducted a meta-analysis of randomized controlled trials (RCTs) involving the use of supplemental intravenous lidocaine in spine surgery. We developed a comprehensive search strategy to adequately screen for randomized controlled trials involving intravenous lidocaine in spine surgery. Continuous outcomes included postoperative opiate consumption and postoperative pain scores. Dichotomous outcomes included nausea, vomiting, pneumonia, delirium, and wound infection. RESULTS: A total of 3 RCTs comprising 235 patients were selected for inclusion in the meta-analysis. Cumulative morphine consumption at 48 h was not statistically significant between lidocaine and control groups. Postoperative pain was not statistically significant at any measured time points in the first and second day postoperatively. There was no statistical difference in postoperative complications including nausea, vomiting, pneumonia, delirium, or surgical site infection. CONCLUSION: Our results indicated that current literature does not support the use of intravenous lidocaine as an adjunctive measure of pain management after spine surgery. Given the relatively few numbers of studies in this field, further randomized controlled trials are needed to make a definitive conclusion on the effectiveness of lidocaine in spine surgery patients. |
format | Online Article Text |
id | pubmed-8819964 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-88199642022-02-08 Intravenous lidocaine in spine surgery: A meta-analysis of randomized controlled trials Haratian, Aryan Musa, Arif Field, Ryan Farhan, Saif Bennett, Collin Cooke, Christopher Patel, Rakesh D. Aleem, Ilyas S. Eichler, Martin C. Rajalingam, Karan Lee, Carlin Bederman, Samuel N Am Spine Soc J Systematic Reviews/Meta-analyses BACKGROUND: This study aimed to evaluate the role of intravenous lidocaine as a supplemental pain control modality in patients undergoing spine surgery. METHODS: We conducted a meta-analysis of randomized controlled trials (RCTs) involving the use of supplemental intravenous lidocaine in spine surgery. We developed a comprehensive search strategy to adequately screen for randomized controlled trials involving intravenous lidocaine in spine surgery. Continuous outcomes included postoperative opiate consumption and postoperative pain scores. Dichotomous outcomes included nausea, vomiting, pneumonia, delirium, and wound infection. RESULTS: A total of 3 RCTs comprising 235 patients were selected for inclusion in the meta-analysis. Cumulative morphine consumption at 48 h was not statistically significant between lidocaine and control groups. Postoperative pain was not statistically significant at any measured time points in the first and second day postoperatively. There was no statistical difference in postoperative complications including nausea, vomiting, pneumonia, delirium, or surgical site infection. CONCLUSION: Our results indicated that current literature does not support the use of intravenous lidocaine as an adjunctive measure of pain management after spine surgery. Given the relatively few numbers of studies in this field, further randomized controlled trials are needed to make a definitive conclusion on the effectiveness of lidocaine in spine surgery patients. Elsevier 2021-09-06 /pmc/articles/PMC8819964/ /pubmed/35141644 http://dx.doi.org/10.1016/j.xnsj.2021.100079 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Systematic Reviews/Meta-analyses Haratian, Aryan Musa, Arif Field, Ryan Farhan, Saif Bennett, Collin Cooke, Christopher Patel, Rakesh D. Aleem, Ilyas S. Eichler, Martin C. Rajalingam, Karan Lee, Carlin Bederman, Samuel Intravenous lidocaine in spine surgery: A meta-analysis of randomized controlled trials |
title | Intravenous lidocaine in spine surgery: A meta-analysis of randomized controlled trials |
title_full | Intravenous lidocaine in spine surgery: A meta-analysis of randomized controlled trials |
title_fullStr | Intravenous lidocaine in spine surgery: A meta-analysis of randomized controlled trials |
title_full_unstemmed | Intravenous lidocaine in spine surgery: A meta-analysis of randomized controlled trials |
title_short | Intravenous lidocaine in spine surgery: A meta-analysis of randomized controlled trials |
title_sort | intravenous lidocaine in spine surgery: a meta-analysis of randomized controlled trials |
topic | Systematic Reviews/Meta-analyses |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8819964/ https://www.ncbi.nlm.nih.gov/pubmed/35141644 http://dx.doi.org/10.1016/j.xnsj.2021.100079 |
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