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Synthesis and cytotoxicity of the boron carrier pentagamaboronon-0-ol for boron neutron capture therapy against breast cancer

Boronic acid-containing curcumin analog, pentagamaboronon-0 (PGB-0), acts as a potential boron-carrier agent but has limited water solubility. Thus, a new compound (PGB-0-ol) with better chemical and pharmacological properties than PGB-0 has been synthesized. Molecular docking was performed using a...

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Detalles Bibliográficos
Autores principales: Utomo, Rohmad Yudi, Wulandari, Febri, Novitasari, Dhania, Susidarti, Ratna Asmah, Kirihata, Mitsunori, Hermawan, Adam, Meiyanto, Edy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820341/
https://www.ncbi.nlm.nih.gov/pubmed/35223445
http://dx.doi.org/10.4103/japtr.japtr_220_21