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Wearable Wireless Power Systems for “ME-BIT” Magnetoelectric-Powered Bio Implants

OBJECTIVE. Compared to biomedical devices with implanted batteries, wirelessly powered technologies can be longer-lasting, less invasive, safer, and can be miniaturized to access difficult-to-reach areas of the body. Magnetic fields are an attractive wireless power transfer (WPT) modality for such b...

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Autores principales: Alrashdan, Fatima T., Chen, Joshua C., Singer, Amanda, Avants, Benjamin W., Yang, Kaiyuan, Robinson, Jacob T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820397/
https://www.ncbi.nlm.nih.gov/pubmed/34229314
http://dx.doi.org/10.1088/1741-2552/ac1178
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author Alrashdan, Fatima T.
Chen, Joshua C.
Singer, Amanda
Avants, Benjamin W.
Yang, Kaiyuan
Robinson, Jacob T.
author_facet Alrashdan, Fatima T.
Chen, Joshua C.
Singer, Amanda
Avants, Benjamin W.
Yang, Kaiyuan
Robinson, Jacob T.
author_sort Alrashdan, Fatima T.
collection PubMed
description OBJECTIVE. Compared to biomedical devices with implanted batteries, wirelessly powered technologies can be longer-lasting, less invasive, safer, and can be miniaturized to access difficult-to-reach areas of the body. Magnetic fields are an attractive wireless power transfer (WPT) modality for such bioelectronic applications because they suffer negligible absorption and reflection in biological tissues. However, current solutions using magnetic fields for mm-sized implants either operate at high frequencies (>500 kHz) or require high magnetic field strengths (>10 mT), which restricts the amount of power that can be transferred safely through tissue and limits the development of wearable power transmitter systems. Magnetoelectric (ME) materials have recently been shown to provide a wireless power solution for mm-sized neural stimulators. These ME transducers convert low magnitude (<1 mT) and low-frequency (~300 kHz) magnetic fields into electric fields that can power custom integrated circuits or stimulate nearby tissue. APPROACH. Here we demonstrate a battery-powered wearable magnetic field generator that can power a miniaturized MagnetoElectric-powered Bio ImplanT “ME-BIT” that functions as a neural stimulator. The wearable transmitter weighs less than 0.5 lbs and has an approximate battery life of 37 hr. MAIN RESULTS. We demonstrate the ability to power a millimeter-sized prototype “ME-BIT” at a distance of 4 cm with enough energy to electrically stimulate a rat sciatic nerve. We also find that the system performs well under translational misalignment and identify safe operating ranges according to the specific absorption rate limits set by the IEEE Std 95.1–2019. SIGNIFICANCE. These results validate the feasibility of a wearable system that can power miniaturized magnetoelectric implants that can be used for different neuromodulation applications.
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spelling pubmed-88203972022-02-07 Wearable Wireless Power Systems for “ME-BIT” Magnetoelectric-Powered Bio Implants Alrashdan, Fatima T. Chen, Joshua C. Singer, Amanda Avants, Benjamin W. Yang, Kaiyuan Robinson, Jacob T. J Neural Eng Article OBJECTIVE. Compared to biomedical devices with implanted batteries, wirelessly powered technologies can be longer-lasting, less invasive, safer, and can be miniaturized to access difficult-to-reach areas of the body. Magnetic fields are an attractive wireless power transfer (WPT) modality for such bioelectronic applications because they suffer negligible absorption and reflection in biological tissues. However, current solutions using magnetic fields for mm-sized implants either operate at high frequencies (>500 kHz) or require high magnetic field strengths (>10 mT), which restricts the amount of power that can be transferred safely through tissue and limits the development of wearable power transmitter systems. Magnetoelectric (ME) materials have recently been shown to provide a wireless power solution for mm-sized neural stimulators. These ME transducers convert low magnitude (<1 mT) and low-frequency (~300 kHz) magnetic fields into electric fields that can power custom integrated circuits or stimulate nearby tissue. APPROACH. Here we demonstrate a battery-powered wearable magnetic field generator that can power a miniaturized MagnetoElectric-powered Bio ImplanT “ME-BIT” that functions as a neural stimulator. The wearable transmitter weighs less than 0.5 lbs and has an approximate battery life of 37 hr. MAIN RESULTS. We demonstrate the ability to power a millimeter-sized prototype “ME-BIT” at a distance of 4 cm with enough energy to electrically stimulate a rat sciatic nerve. We also find that the system performs well under translational misalignment and identify safe operating ranges according to the specific absorption rate limits set by the IEEE Std 95.1–2019. SIGNIFICANCE. These results validate the feasibility of a wearable system that can power miniaturized magnetoelectric implants that can be used for different neuromodulation applications. 2021-07-26 /pmc/articles/PMC8820397/ /pubmed/34229314 http://dx.doi.org/10.1088/1741-2552/ac1178 Text en https://creativecommons.org/licenses/by/3.0/As the Version of Record of this article is going to be / has been published on a gold open access basis under a CC BY 3.0 licence, this Accepted Manuscript is available for reuse under a CC BY 3.0 licence immediately. Everyone is permitted to use all or part of the original content in this article, provided that they adhere to all the terms of the licence https://creativecommons.org/licenses/by/3.0 (https://creativecommons.org/licenses/by/3.0/) Although reasonable endeavours have been taken to obtain all necessary permissions from third parties to include their copyrighted content within this article, their full citation and copyright line may not be present in this Accepted Manuscript version. Before using any content from this article, please refer to the Version of Record on IOPscience once published for full citation and copyright details, as permissions may be required. All third party content is fully copyright protected and is not published on a gold open access basis under a CC BY licence, unless that is specifically stated in the figure caption in the Version of Record.
spellingShingle Article
Alrashdan, Fatima T.
Chen, Joshua C.
Singer, Amanda
Avants, Benjamin W.
Yang, Kaiyuan
Robinson, Jacob T.
Wearable Wireless Power Systems for “ME-BIT” Magnetoelectric-Powered Bio Implants
title Wearable Wireless Power Systems for “ME-BIT” Magnetoelectric-Powered Bio Implants
title_full Wearable Wireless Power Systems for “ME-BIT” Magnetoelectric-Powered Bio Implants
title_fullStr Wearable Wireless Power Systems for “ME-BIT” Magnetoelectric-Powered Bio Implants
title_full_unstemmed Wearable Wireless Power Systems for “ME-BIT” Magnetoelectric-Powered Bio Implants
title_short Wearable Wireless Power Systems for “ME-BIT” Magnetoelectric-Powered Bio Implants
title_sort wearable wireless power systems for “me-bit” magnetoelectric-powered bio implants
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820397/
https://www.ncbi.nlm.nih.gov/pubmed/34229314
http://dx.doi.org/10.1088/1741-2552/ac1178
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