Cargando…

Molecular Modeling and Preliminary Clinical Data Suggesting Antiviral Activity for Chlorpheniramine (Chlorphenamine) Against COVID-19

Chlorpheniramine maleate, a widely used over-the-counter antihistamine, has been identified as a structural analog of aminoquinolines known to possess antiviral activity against the Betacoronavirus severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that causes coronavirus disease 2019 (COV...

Descripción completa

Detalles Bibliográficos
Autor principal:	Black, Shaun D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cureus 2022
Materias:	Infectious Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820487/ https://www.ncbi.nlm.nih.gov/pubmed/35154957 http://dx.doi.org/10.7759/cureus.20980

Ejemplares similares

Chlorpheniramine Maleate Throat Spray for the Treatment of COVID-19-Induced Acute Viral Pharyngitis: Case Series
por: Tesch, Mari L, et al.
Publicado: (2023)

The Rise of SARS-CoV-2 (COVID-19) Omicron Subvariant Pathogenicity
por: DeGrasse, David C, et al.
Publicado: (2023)

Antiviral Activity of Svarnvir-IV Tablet Assayed for Activity Against SARS-CoV-2 In Vitro
por: Reddy, K. Ramachandra, et al.
Publicado: (2023)

Basrah Preliminary Experience With COVID-19: A Report on 6404 Patients
por: Hammadi, Saad, et al.
Publicado: (2021)

The Management of Wrist Fractures During COVID-19: A Preliminary Report
por: Okereke, Isaac C, et al.
Publicado: (2021)

Platform adaptive trial of novel antivirals for early treatment of COVID-19 In the community (PANORAMIC): protocol for a randomised, controlled, open-label, adaptive platform trial of community novel antiviral treatment of COVID-19 in people at increased risk of more severe disease
por: Gbinigie, Oghenekome, et al.
Publicado: (2023)

An Early and Preliminary Assessment of the Clinical Severity of the Emerging SARS-CoV-2 Omicron Variants in Maharashtra, India
por: Karyakarte, Rajesh P, et al.
Publicado: (2022)

Efficacy and safety of three new oral antiviral treatment (molnupiravir, fluvoxamine and Paxlovid) for COVID-19：a meta-analysis
por: Wen, Wen, et al.
Publicado: (2022)

Factors associated with non-persistence to oral and inhaled antiviral therapies for seasonal influenza: a secondary analysis of a double-blind, multicentre, randomised clinical trial
por: Flicoteaux, Remi, et al.
Publicado: (2017)

Multimodal Treatment of Hepatocellular Carcinoma in Patients With Hepatitis C Virus Infection Treated With Direct-Acting Antivirals
por: Mercan-Stanciu, Adriana, et al.
Publicado: (2022)

Managing COVID-19 infection in a Young Acute Myeloid Leukemia Patient Successfully With Antiviral and Granulocyte Colony Stimulating Factor: Playing on a Sticky Wicket
por: Talwar, Dhruv, et al.
Publicado: (2021)

Safety and efficacy of hydroxychloroquine as prophylactic against COVID-19 in healthcare workers: a meta-analysis of randomised clinical trials
por: Hong, Hwanhee, et al.
Publicado: (2023)

Oral health and the presence of infectious microorganisms in hospitalized patients: a preliminary observational study
por: Cruz, Adriana Silva da Costa, et al.
Publicado: (2022)

Human Plasma Significantly Reduces Bacteriophage Infectivity Against Staphylococcus aureus Clinical Isolates
por: Shinde, Prajakta, et al.
Publicado: (2022)

The Burden and Characteristics of Post-COVID-19 Conditions Among Laboratory-Confirmed Delta and Omicron COVID-19 Cases: A Preliminary Study From Maharashtra, India
por: Karyakarte, Rajesh P, et al.
Publicado: (2023)

A Preliminary Study Into the Significance of Intrarenal Reflux in BK Virus Nephropathy After Kidney Transplantation
por: Kawanishi, Kunio, et al.
Publicado: (2016)

Chlorhexidine oral rinses for symptomatic COPD: a randomised, blind, placebo-controlled preliminary study
por: Pragman, Alexa A, et al.
Publicado: (2021)

Psychological stress; knowledge, attitude and practice and acceptance of antiviral therapy in pregnant women with hepatitis B in Zhejiang, China: a case comparison study
por: Liu, Xiaoxiao, et al.
Publicado: (2022)

A Rare Case of Staphylococcus caprae-Caused Periprosthetic Joint Infection Following Total Hip Arthroplasty: A Literature Review and Antibiotic Treatment Algorithm Suggestion
por: Domashenko, Philip, et al.
Publicado: (2023)

Vaccination against COVID-19 and society’s return to normality in England: a modelling study of impacts of different types of naturally acquired and vaccine-induced immunity
por: Song, Fujian, et al.
Publicado: (2021)

Integrating Public Health Surveillance and Environmental Data to Model Presence of Histoplasma in the United States
por: Hepler, Staci A., et al.
Publicado: (2022)

Effect of vaccination on the case fatality rate for COVID-19 infections 2020–2021: multivariate modelling of data from the US Department of Veterans Affairs
por: Murata, Glen H, et al.
Publicado: (2022)

An Old Defence Against New Infections: The Open-Air Factor and COVID-19
por: Hobday, Richard, et al.
Publicado: (2022)

A Systematic Review and Meta-analysis of Optimized CMV Preemptive Therapy and Antiviral Prophylaxis for CMV Disease Prevention in CMV High-Risk (D+R-) Kidney Transplant Recipients
por: Kumar, Lakshin, et al.
Publicado: (2023)

The effect of dose on the antimalarial efficacy of artesunate-mefloquine against Plasmodium falciparum malaria: a protocol for systematic review and individual patient data (IPD) meta-analysis
por: Mansoor, Rashid, et al.
Publicado: (2019)

Impact of prior probabilities of MRSA as an infectious agent on the accuracy of the emerging molecular diagnostic tests: a model simulation
por: Zilberberg, Marya D, et al.
Publicado: (2012)

Clinical outcomes, molecular epidemiology and resistance mechanisms of multidrug-resistant Pseudomonas aeruginosa isolated from bloodstream infections from Qatar
por: Sid Ahmed, Mazen A., et al.
Publicado: (2021)

Identification of spinal tuberculosis subphenotypes using routine clinical data: a study based on unsupervised machine learning
por: Yao, Yuanlin, et al.
Publicado: (2023)

First malaria infections in a cohort of infants in Benin: biological, environmental and genetic determinants. Description of the study site, population methods and preliminary results
por: Le Port, Agnès, et al.
Publicado: (2012)

Effectiveness of Containment Measures Against COVID-19 in Singapore: Implications for Other National Containment Efforts
por: Pung, Rachael, et al.
Publicado: (2020)

Social Data: An Underutilized Metric for Determining Participation in COVID-19 Vaccinations
por: McCarthy, Alec D, et al.
Publicado: (2021)

Lipid intensive drug therapy for sepsis pilot: A Bayesian phase I clinical trial
por: Guirgis, Faheem W., et al.
Publicado: (2020)

The Role of Vitamin C in Human Immunity and Its Treatment Potential Against COVID-19: A Review Article
por: Moore, Austin, et al.
Publicado: (2023)

Impact of comprehensive molecular testing to reduce antibiotic use in community-acquired pneumonia (RADICAP): a randomised, controlled, phase IV clinical trial protocol
por: Abelenda-Alonso, Gabriela, et al.
Publicado: (2020)

Accelerating clinical development of a live attenuated vaccine against Salmonella Paratyphi A (VASP): study protocol for an observer-participant-blind randomised control trial of a novel oral vaccine using a human challenge model of Salmonella Paratyphi A infection in healthy adult volunteers
por: McCann, Naina, et al.
Publicado: (2023)

Human Leukocyte Antigen (HLA) Class I Susceptible Alleles Against COVID-19 Increase Both Infection and Severity Rate
por: Ishii, Tomoo
Publicado: (2020)

COVID-19 in Oromia Region of Ethiopia: a review of the first 6 months’ surveillance data
por: Gudina, Esayas Kebede, et al.
Publicado: (2021)

Mask effectiveness against viral illnesses in health care professionals
por: Kraus, Chadd K.
Publicado: (2021)

Prognostic prediction models for clinical outcomes in patients diagnosed with visceral leishmaniasis: protocol for a systematic review
por: Wilson, James, et al.
Publicado: (2023)

Factors associated with the severity of COVID‐19 outcomes in people with neuromuscular diseases: Data from the International Neuromuscular COVID‐19 Registry
por: Pizzamiglio, Chiara, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6umevbiokrhdoolo8duu9fud4l