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Cell-free tumor DNA, CA125 and HE4 for the objective assessment of tumor burden in patients with advanced high-grade serous ovarian cancer

BACKGROUND: The present prospective study aimed at determining the impact of cell-free tumor DNA (ct-DNA), CA125 and HE4 from blood and ascites for quantification of tumor burden in patients with advanced high-grade serous epithelial ovarian cancer (EOC). METHODS: Genomic DNA was extracted from tumo...

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Detalles Bibliográficos
Autores principales: Heitz, Florian, Lakis, Sotirios, Harter, Philipp, Heikaus, Sebastian, Sehouli, Jalid, Talwar, Jatin, Menon, Roopika, Ataseven, Beyhan, Bertrand, Miriam, Schneider, Stephanie, Mariotti, Erika, Bommert, Mareike, Müller, Judith N., Prader, Sonia, Leenders, Frauke, Hengsbach, Alexandra, Gloeckner, Christian, Braicu, Elena Ioana, Heukamp, Lukas C., du Bois, Andreas, Heuckmann, Johannes M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820624/
https://www.ncbi.nlm.nih.gov/pubmed/35130283
http://dx.doi.org/10.1371/journal.pone.0262770

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