Conserved Neutralizing Epitopes on the N-Terminal Domain of Variant SARS-CoV-2 Spike Proteins

SARS-CoV-2 infection or vaccination produces neutralizing antibody responses that contribute to better clinical outcomes. The receptor binding domain (RBD) and the N-terminal domain (NTD) of the spike trimer (S) constitute the two major neutralizing targets for the antibody system. Neutralizing anti...

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Detalles Bibliográficos
Autores principales: Wang, Zijun, Muecksch, Frauke, Cho, Alice, Gaebler, Christian, Hoffmann, Hans-Heinrich, Ramos, Victor, Zong, Shuai, Cipolla, Melissa, Johnson, Briana, Schmidt, Fabian, DaSilva, Justin, Bednarski, Eva, Tanfous, Tarek Ben, Raspe, Raphael, Yao, Kaihui, Lee, Yu E., Chen, Teresia, Turroja, Martina, Milard, Katrina G., Dizon, Juan, Kaczynska, Anna, Gazumyan, Anna, Oliveira, Thiago Y., Rice, Charles M., Caskey, Marina, Bieniasz, Paul D., Hatziioannou, Theodora, Barnes, Christopher O., Nussenzweig, Michel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820657/
https://www.ncbi.nlm.nih.gov/pubmed/35132412
http://dx.doi.org/10.1101/2022.02.01.478695

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