A model for network-based identification and pharmacological targeting of aberrant, replication-permissive transcriptional programs induced by viral infection

Mostrar otras versiones (1)

Precise characterization and targeting of host cell transcriptional machinery hijacked by viral infection remains challenging. Here, we show that SARS-CoV-2 hijacks the host cell transcriptional machinery to induce a phenotypic state amenable to its replication. Specifically, analysis of Master Regu...

Descripción completa

Detalles Bibliográficos
Autores principales: Laise, Pasquale, Stanifer, Megan L., Bosker, Gideon, Sun, Xiaoyun, Triana, Sergio, Doldan, Patricio, La Manna, Federico, De Menna, Marta, Realubit, Ronald B., Pampou, Sergey, Karan, Charles, Alexandrov, Theodore, Kruithof-de Julio, Marianna, Califano, Andrea, Boulant, Steeve, Alvarez, Mariano J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820669/
https://www.ncbi.nlm.nih.gov/pubmed/35132404
http://dx.doi.org/10.21203/rs.3.rs-1287631/v1
Mostrar todas las versiones(2)

Ejemplares similares