Reducing host aldose reductase activity promotes neuronal differentiation of transplanted neural stem cells at spinal cord injury sites and facilitates locomotion recovery

Neural stem cell (NSC) transplantation is a promising strategy for replacing lost neurons following spinal cord injury. However, the survival and differentiation of transplanted NSCs is limited, possibly owing to the neurotoxic inflammatory microenvironment. Because of the important role of glucose...

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Detalles Bibliográficos
Autores principales: Zhang, Kun, Lu, Wen-Can, Zhang, Ming, Zhang, Qian, Xian, Pan-Pan, Liu, Fang-Fang, Chen, Zhi-Yang, Kim, Chung Sookja, Wu, Sheng-Xi, Tao, Hui-Ren, Wang, Ya-Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820702/
https://www.ncbi.nlm.nih.gov/pubmed/35017443
http://dx.doi.org/10.4103/1673-5374.330624

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