Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands

Nicotinic partial agonists provide an accepted aid for smoking cessation and thus contribute to decreasing tobacco-related disease. Improved drugs constitute a continued area of study. However, there remains no reductionist method to examine the cellular and subcellular pharmacokinetic properties of...

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Detalles Bibliográficos
Autores principales: Nichols, Aaron L, Blumenfeld, Zack, Fan, Chengcheng, Luebbert, Laura, Blom, Annet EM, Cohen, Bruce N, Marvin, Jonathan S, Borden, Philip M, Kim, Charlene H, Muthusamy, Anand K, Shivange, Amol V, Knox, Hailey J, Campello, Hugo Rego, Wang, Jonathan H, Dougherty, Dennis A, Looger, Loren L, Gallagher, Timothy, Rees, Douglas C, Lester, Henry A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820738/
https://www.ncbi.nlm.nih.gov/pubmed/34982029
http://dx.doi.org/10.7554/eLife.74648

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