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Drugging the undruggable: activity-based protein profiling offers opportunities for targeting the KLK activome
The vast majority of the human proteome is yet to be functionally characterized thus hindering ongoing investigations on potential drug resistance mechanisms and advanced treatment options. Chemical proteomics is a powerful solution for enzyme profiling and the development of next generation cancer...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820805/ https://www.ncbi.nlm.nih.gov/pubmed/35129066 http://dx.doi.org/10.1080/15384047.2022.2033059 |