BMS-470539 Attenuates Oxidative Stress and Neuronal Apoptosis via MC1R/cAMP/PKA/Nurr1 Signaling Pathway in a Neonatal Hypoxic-Ischemic Rat Model

Neuronal apoptosis induced by oxidative stress plays an important role in the pathogenesis and progression of hypoxic-ischemic encephalopathy (HIE). Previous studies reported that activation of melanocortin-1 receptor (MC1R) exerts antioxidative stress, antiapoptotic, and neuroprotective effects in...

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Detalles Bibliográficos
Autores principales: Yu, Shufeng, Doycheva, Desislava Met, Gamdzyk, Marcin, Gao, Yuanyuan, Guo, Yong, Travis, Zachary D., Tang, Jiping, Chen, Wen-Xiong, Zhang, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820941/
https://www.ncbi.nlm.nih.gov/pubmed/35140838
http://dx.doi.org/10.1155/2022/4054938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8820941/
https://www.ncbi.nlm.nih.gov/pubmed/35140838
http://dx.doi.org/10.1155/2022/4054938

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